Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory tetrapeptide tuftsin, extended with a Pro-Gly-Pro motif that improves enzymatic stability. For research teams investigating neuropeptide signaling, anxiolytic pathways, and neuroimmune interactions, it offers a well-characterized tool compound with an extensive Russian preclinical literature. Puritide Research supplies Selank as a high-purity, research-use-only material, synthesized for in vitro and animal-model work and backed by third-party-verified certificates of analysis so your data rests on consistent, documented quality.
Product Specifications
- Application
- Neuropeptide, anxiolytic pathway, and neuroimmune signaling research
- Appearance
- Solid, white lyophilized powder in a sealed glass vial
- Chemical Formula
- C33H57N11O9
- PubChem SID
- 11765600
- CAS Number
- 129954-34-3
- Molecular Weight
- ~751.88 g/mol
- Synonyms
- Selank, TP-7, Tuftsin analog, Heptapeptide Selank, Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
- Storage
- Store at ≤25°C, sealed, away from heat, light, and moisture. For extended storage, keep lyophilized and refrigerated or frozen.
What Is Selank?
Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences as a stabilized analog of tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) with immunomodulatory activity. The added C-terminal Pro-Gly-Pro sequence is intended to slow enzymatic degradation and extend the molecule's stability relative to the parent peptide.
In experimental settings, Selank is studied for its influence on neuropeptide signaling, GABAergic and monoaminergic systems, and neuroimmune pathways. Researchers use it to explore anxiolytic-related mechanisms, gene-expression changes, and peptide pharmacology within controlled cell-culture and animal models.
Present understanding derives from in vitro assays and animal models, together with clinical research conducted primarily in Russia. Findings should be interpreted within their experimental context and not treated as established outcomes. Puritide Research supplies Selank strictly for laboratory use; it is not approved for human or veterinary application.
Puritide Research supplies Selank strictly for laboratory research use. Not for human or veterinary use.
Research Use Only
