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DihexaResearch Use Only
Cognitive / nootropic

Dihexa

PR-DIHEXA · ≥99%

Dihexa (PNB-0408) is a small-molecule oligopeptide derived from angiotensin IV, engineered to potentiate hepatocyte growth factor (HGF) signaling at its receptor c-Met.

Quantity & savings
1
10mg · $55.00
1
  • ✓Lyophilized and sealed under sterile, controlled conditions
  • ✓Purity ≥99%, mass-spectrometry and analytical HPLC verified
  • ✓Fully traceable from first synthesis to sealed vial
  • ✓Certificate of analysis (CoA) included with every vial

Ships cold-safe · discreet packaging · tracked delivery.

Lab results

Certificate of Analysis 99.54%Endotoxin Report PASSVerify this lotAuthentic →

Research Use Only

These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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About Dihexa

Dihexa (PNB-0408) is a small-molecule oligopeptide derived from angiotensin IV, engineered to potentiate hepatocyte growth factor (HGF) signaling at its receptor c-Met. For research teams studying synaptogenesis and neurotrophic signaling, it offers a metabolically stabilized model compound with high reported activity in cellular assays. Puritide Research supplies Dihexa as a high-purity, research-use-only material, synthesized for in vitro and animal-model work and backed by third-party-verified certificates of analysis so your data rests on consistent, documented quality.

Available Sizes

  • ›Dihexa 10 mg Vial

Product Specifications

Application
Neurotrophic and synaptogenesis pathway research (HGF / c-Met)
Appearance
Solid, white lyophilized powder in a sealed glass vial
Chemical Formula
C27H44N4O5
PubChem SID
129010512
CAS Number
1401708-83-5
Molecular Weight
~504.66 g/mol
Synonyms
Dihexa, PNB-0408, N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, N-hexanoyl-Tyr-Ile-AHA
Storage
Store at ≤25°C, sealed, away from heat, light, and moisture. For extended storage, keep lyophilized and refrigerated or frozen.

What Is Dihexa?

Dihexa (PNB-0408), chemically N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, is a modified oligopeptide developed from the angiotensin IV framework. Structural modifications, an N-terminal hexanoic acid cap and a C-terminal aminohexanoic amide, were introduced to improve metabolic stability and membrane permeability relative to the parent peptide.

In experimental settings, Dihexa is studied for its reported ability to bind hepatocyte growth factor (HGF) and augment its interaction with the c-Met receptor, a pathway associated with cell growth, motility, and synapse formation. Cellular assays have described it as a highly potent enhancer of neurotrophic activity, making it a subject of interest for synaptogenesis and cognition research in model systems.

Present understanding of Dihexa derives from in vitro assays and animal models, and observations should be interpreted within their experimental context rather than treated as established physiological or clinical outcomes. Puritide Research supplies Dihexa strictly for laboratory use; it is not approved for human or veterinary application.

Puritide Research supplies Dihexa strictly for laboratory research use. Not for human or veterinary use.

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