Research Use Only

Lab results

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Research Use Only

These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

AMPK activationmitochondrial-nuclear signalling

MOTS-C

Name: MOTS-C 10mg
Brand: Puritide Research
SKU: PR-MOTSC
Price: 35.00 USD
Availability: InStock

PR-MOTSC · ≥99%

Mitochondrial-derived 16-amino-acid peptide studied in AMPK and metabolic-stress signalling. Lyophilized.

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MOTS-C

Research use only

✓Lyophilized and sealed under sterile, controlled conditions
✓Purity ≥99%, mass-spectrometry and analytical HPLC verified
✓Fully traceable from first synthesis to sealed vial
✓Certificate of analysis (CoA) included with every vial

Ships cold-safe · discreet packaging · tracked delivery.

Lab results

Certificate of Analysis 99.52%Endotoxin Report PASS Verify this lotAuthentic →

Research Use Only

About MOTS-c

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the 12S ribosomal RNA region of mitochondrial DNA rather than in the nuclear genome. This unusual origin has made it a focal point for laboratories studying mitochondrial signaling, metabolic regulation, and cellular stress responses. Puritide Research supplies MOTS-c as a high-purity, research-use-only material, synthesized for in vitro and animal-model work and backed by third-party-verified certificates of analysis so your data rests on consistent, documented quality.

Available Sizes

›MOTS-c 10 mg Vial
›MOTS-c 40 mg Vial

Product Specifications

Application: Mitochondrial signaling and metabolic pathway research
Appearance: Solid, white lyophilized powder in a sealed glass vial
Chemical Formula: C101H152N28O22S2
PubChem SID: 146675088
CAS Number: 1627580-64-6
Molecular Weight: ~2174.6 g/mol
Synonyms: MOTS-c, Mitochondrial ORF of the 12S rRNA type-c, mitochondrial-derived peptide, MDP
Storage: Store at ≤25°C, sealed, away from heat, light, and moisture. For extended storage, keep lyophilized and refrigerated or frozen.

What Is MOTS-c?

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a short peptide first reported in 2015 that is encoded within mitochondrial DNA. It belongs to a small class of mitochondrial-derived peptides that appear to act as signaling molecules connecting mitochondrial status to the rest of the cell.

In experimental settings, MOTS-c is investigated for its association with cellular metabolism, the AMPK signaling axis, and adaptive responses to metabolic stress. Because it originates from the mitochondrial genome, it is often studied as a model for retrograde signaling, communication from mitochondria to the nucleus.

Present understanding derives from in vitro assays and animal models. Findings should be interpreted within their experimental context and not treated as established clinical outcomes. Puritide Research supplies MOTS-c strictly for laboratory use; it is not approved for human or veterinary application.

Puritide Research supplies MOTS-c strictly for laboratory research use. Not for human or veterinary use.

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Certificate of AnalysisLOT #ADI154630-79E · 99.50%PASS

$125.00

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