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5-Amino-1MQResearch Use Only
Longevity / mitochondrial

5-Amino-1MQ

PR-5AMINO1MQ · ≥99%

5-Amino-1MQ is a small-molecule, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme increasingly studied for its role in cellular energy metabolism.

Quantity & savings
1
50mg · $175.00
1
  • ✓Lyophilized and sealed under sterile, controlled conditions
  • ✓Purity ≥99%, mass-spectrometry and analytical HPLC verified
  • ✓Fully traceable from first synthesis to sealed vial
  • ✓Certificate of analysis (CoA) included with every vial

Ships cold-safe · discreet packaging · tracked delivery.

Lab results

Certificate of Analysis 99.83%Endotoxin Report PASSVerify this lotAuthentic →

Research Use Only

These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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About 5-Amino-1MQ

5-Amino-1MQ is a small-molecule, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme increasingly studied for its role in cellular energy metabolism. For research teams investigating NAD+ regulation, adipose biology, and methylation flux, it offers a well-characterized chemical probe with a defined enzymatic target. Puritide Research supplies 5-Amino-1MQ as a high-purity, research-use-only material, prepared for in vitro and animal-model work and backed by third-party-verified certificates of analysis so your data rests on consistent, documented quality.

Available Sizes

  • ›5-Amino-1MQ 50 mg Vial

Product Specifications

Application
NNMT inhibition and NAD+ / methylation metabolism research
Appearance
Solid, white to off-white lyophilized powder in a sealed glass vial
Chemical Formula
C10H11N2+ (cation); C10H11IN2 (iodide salt as supplied)
PubChem SID
950107
CAS Number
685079-15-6 (cation); 42464-96-0 (iodide salt)
Molecular Weight
~159.21 g/mol (cation); ~286.11 g/mol (iodide salt)
Synonyms
5-Amino-1MQ, 5-Amino-1-methylquinolinium, 1-methylquinolin-1-ium-5-amine, NNMTi, 5-Amino-1MQ iodide
Storage
Store at ≤25°C, sealed, away from heat, light, and moisture. For extended storage, keep desiccated and refrigerated or frozen.

What Is 5-Amino-1MQ?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small molecule that functions as a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). Because it carries a permanent positive charge on the quinolinium nitrogen, it is typically handled and supplied as a salt, most commonly the iodide, with the cation and the salt form carrying distinct molecular weights and CAS identifiers.

In experimental settings, 5-Amino-1MQ is used to interrogate the NNMT pathway, which sits at the intersection of nicotinamide handling, NAD+ availability, and S-adenosylmethionine (SAM)-dependent methylation. By reducing NNMT activity in research models, investigators can study how methylation flux and NAD+ pools respond, particularly in adipocyte and metabolic-tissue systems.

Present understanding derives from enzymatic assays, cell-culture studies, and rodent models. Findings should be interpreted within their experimental context and not treated as established clinical outcomes. Puritide Research supplies 5-Amino-1MQ strictly for laboratory use; it is not approved for human or veterinary application.

Puritide Research supplies 5-Amino-1MQ strictly for laboratory research use. Not for human or veterinary use.

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