Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) studied as a selective growth hormone secretagogue and agonist of the ghrelin receptor (GHS-R1a). Described in the literature as one of the first secretagogues to stimulate growth hormone release with a selectivity approaching that of GHRH, without markedly engaging cortisol or prolactin pathways, it is a widely used tool for investigating the growth hormone axis. Puritide Research supplies Ipamorelin as a high-purity, research-use-only material, synthesized for in vitro and animal-model work and backed by third-party-verified certificates of analysis.
Available Sizes
- ›Ipamorelin 5 mg Vial
- ›Ipamorelin 10 mg Vial
Product Specifications
- Application
- Growth hormone secretagogue and ghrelin receptor (GHS-R1a) signaling research
- Appearance
- Solid, white lyophilized powder in a sealed glass vial
- Chemical Formula
- C38H49N9O5
- CAS Number
- 170851-70-4
- Molecular Weight
- ~711.85 g/mol
- Synonyms
- Ipamorelin, NNC 26-0161, GHS pentapeptide
- Storage
- Store at ≤25°C, sealed, away from heat, light, and moisture. For extended storage, keep lyophilized and refrigerated or frozen.
What Is Ipamorelin?
Ipamorelin is a synthetic pentapeptide derived structurally from the growth hormone-releasing peptide GHRP-1. It carries the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 and functions as an agonist of the growth hormone secretagogue receptor (GHS-R1a), the same receptor targeted by the endogenous hormone ghrelin.
What distinguishes Ipamorelin in the research literature is its reported selectivity: it stimulates growth hormone release from pituitary models while producing comparatively little effect on the secretion of other hormones such as cortisol and prolactin. This selectivity makes it a clean tool for isolating GH-axis signaling in experimental systems.
Present understanding derives from in vitro assays and animal models. Findings should be interpreted within their experimental context and not treated as established clinical outcomes. Puritide Research supplies Ipamorelin strictly for laboratory use; it is not approved for human or veterinary application.
Puritide Research supplies Ipamorelin strictly for laboratory research use. Not for human or veterinary use.
Research Use Only
